Product Data Sheet
[Ala17]-MCH
Catalog No. A61612
[Ala17]-MCH is a selective ligand for the melanin-concentrating hormone receptor 1 (MCHR1), exhibiting a Ki value of 0.16 nM, indicating strong affinity compared to MCHR2, which has a Ki of 34 nM. The Eu3+ chelate-labeled form demonstrates high binding affinity for MCHR1 with a Kd of 0.37 nM, while showing negligible interaction with MCHR2. This compound is valuable for research applications involving MCHR1-mediated pathways, particularly in the study of neuropeptide signaling and metabolic regulation.
Chemical Information
| Catalog Num | A61612 |
|---|---|
| M. Wt | 2271.71 |
| Formula | C97H155N29O26S4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 359784-84-2 |
| Synonyms | |
| SMILES | O=C1N2C(C(=O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H]([C@H](C)C)C(O)=O)=O)CCC(N)=O)=O)C)=O)CSSC[C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC3=CC=CC=C3)NC([C@H](CC(O)=O)N)=O)=O)CC(O)=O)=O)CCSC)=O)CC(C)C)=O)CCCNC(=N)N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H]([C@@H](C)C)C(=O)N[C@@H](CC4=CC=C(O)C=C4)C(=O)N[C@H]1CCCNC(=N)N)(CCC2)[H] |
Biological Activity
| Description | [Ala17]-MCH is a selective ligand for the melanin-concentrating hormone receptor 1 (MCHR1), exhibiting a Ki value of 0.16 nM, indicating strong affinity compared to MCHR2, which has a Ki of 34 nM. The Eu3+ chelate-labeled form demonstrates high binding affinity for MCHR1 with a Kd of 0.37 nM, while showing negligible interaction with MCHR2. This compound is valuable for research applications involving MCHR1-mediated pathways, particularly in the study of neuropeptide signaling and metabolic regulation. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
