Product Data Sheet
hMCH-1R antagonist 1
Catalog No. A61616
hMCH-1R antagonist 1 is a selective antagonist of the human melanin-concentrating hormone receptor 1 (hMCHR1) with a binding affinity characterized by a KB value of 3.6 nM. This compound demonstrates effective inhibition of hMCHR1 and hMCHR2, with IC50 values of 65 nM and 49 nM, respectively. hMCH-1R antagonist 1 is suitable for investigations into metabolic pathways and the role of melanin-concentrating hormone in various physiological processes.
Chemical Information
| Catalog Num | A61616 |
|---|---|
| M. Wt | 1167.47 |
| Formula | C49H82N16O11S3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 353487-64-6 |
| Synonyms | |
| SMILES | CSCC[C@@H]1NC(=O)[C@H](CSSC[C@H](NC(=O)CCCCNC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)CCCCNC1=O)C(C)C)C(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O |
Biological Activity
| Description | hMCH-1R antagonist 1 is a selective antagonist of the human melanin-concentrating hormone receptor 1 (hMCHR1) with a binding affinity characterized by a KB value of 3.6 nM. This compound demonstrates effective inhibition of hMCHR1 and hMCHR2, with IC50 values of 65 nM and 49 nM, respectively. hMCH-1R antagonist 1 is suitable for investigations into metabolic pathways and the role of melanin-concentrating hormone in various physiological processes. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
