Product Data Sheet
MCH(human, mouse, rat)
Catalog No. A61618
MCH (human, mouse, rat) is a cyclic neuropeptide that functions as an endogenous ligand for the melanin-concentrating hormone receptor (MCH-R). It exhibits high binding affinity with IC50 values of 0.3 nM and 1.5 nM for human MCH-1R and MCH-2R, respectively, and operational EC50 values of 3.9 nM and 88.7 nM. MCH plays a crucial role in regulating appetite as an orexigenic signal and is instrumental in maintaining energy homeostasis and sleep-wake cycles. This reagent is essential for research into obesity, sleep-related disorders, and related metabolic conditions.
Chemical Information
| Catalog Num | A61618 |
|---|---|
| M. Wt | 2386.84 |
| Formula | C105H160N30O26S4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 128315-56-0 |
| Synonyms | Melanin-concentrating hormone(human, mouse, rat) |
| SMILES | C([C@H](NC(=O)[C@H]1NC(=O)C2(N(C(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC3=CC=C(O)C=C3)NC(=O)[C@H]([C@@H](C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCSC)NC(=O)[C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC4=CC=CC=C4)NC([C@H](CC(O)=O)N)=O)=O)CC(O)=O)=O)CCSC)=O)CC(C)C)=O)CCCNC(=N)N)=O)CSSC1)CCC2)[H])C(N[C@H](C(N[C@@H](C(C)C)C(O)=O)=O)CCC(N)=O)=O)C=5C=6C(NC5)=CC=CC6 |
Biological Activity
| Description | MCH (human, mouse, rat) is a cyclic neuropeptide that functions as an endogenous ligand for the melanin-concentrating hormone receptor (MCH-R). It exhibits high binding affinity with IC50 values of 0.3 nM and 1.5 nM for human MCH-1R and MCH-2R, respectively, and operational EC50 values of 3.9 nM and 88.7 nM. MCH plays a crucial role in regulating appetite as an orexigenic signal and is instrumental in maintaining energy homeostasis and sleep-wake cycles. This reagent is essential for research into obesity, sleep-related disorders, and related metabolic conditions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
