AMG-076 free base
Catalog No. A61620

AMG-076 free base is a selective antagonist of the Melanin-Concentrating Hormone Receptor 1 (MCHR1). It has been shown to significantly reduce body weight gain in non-obese mice subjected to a high-fat diet, as well as in diet-induced obese (DIO) mice. This compound is valuable for research into obesity and metabolic disorders, providing insights into the therapeutic potential of targeting MCHR1 in weight management.
Chemical Information
| Catalog Num | A61620 |
|---|---|
| M. Wt | 462.55 |
| Formula | C26H33F3N2O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 693823-79-9 |
| Synonyms | |
| SMILES | O=C(C1(CCN2CC[C@]3([H])CC(NC4=C5C=C(C(F)(F)F)C=C4)=C5[C@H](C)[C@@]3([H])C2)CCCCC1)O |
Biological Activity
| Description | AMG-076 free base is a selective antagonist of the Melanin-Concentrating Hormone Receptor 1 (MCHR1). It has been shown to significantly reduce body weight gain in non-obese mice subjected to a high-fat diet, as well as in diet-induced obese (DIO) mice. This compound is valuable for research into obesity and metabolic disorders, providing insights into the therapeutic potential of targeting MCHR1 in weight management. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


