Product Data Sheet
T-226296
Catalog No. A61623
T-226296 is a selective antagonist of the melanin-concentrating hormone receptor, exhibiting IC50 values of 5.5 nM and 8.6 nM for human and rat SLC-1, respectively. This compound demonstrates potential in modulating weight and metabolic processes, making it useful in research on obesity and insulin resistance. Its oral bioavailability facilitates in vivo studies, providing insights into the role of melanin-concentrating hormone signaling in metabolic disorders.
Chemical Information
| Catalog Num | A61623 |
|---|---|
| M. Wt | 402.50 |
| Formula | C26H27FN2O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 331758-35-1 |
| Synonyms | |
| SMILES | O=C(C1=CC=C(C2=CC=C(C=C2)F)C=C1)NC3=CC=C(CC(CC4)CN(C)C)C4=C3 |
Biological Activity
| Description | T-226296 is a selective antagonist of the melanin-concentrating hormone receptor, exhibiting IC50 values of 5.5 nM and 8.6 nM for human and rat SLC-1, respectively. This compound demonstrates potential in modulating weight and metabolic processes, making it useful in research on obesity and insulin resistance. Its oral bioavailability facilitates in vivo studies, providing insights into the role of melanin-concentrating hormone signaling in metabolic disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
