Product Data Sheet
Bivamelagon
Catalog No. A61630
Bivamelagon is a selective agonist of the melanocortin 4 receptor (MC4R) with an EC50 of 0.562 nM in a luciferase assay and 36.5 nM in a cAMP assay, demonstrating its potent activity. This compound exhibits a Ki value of 65 nM, indicating strong binding affinity to its target. Bivamelagon is valuable for research into metabolic disorders, particularly in the context of obesity and diabetes, providing insights into potential therapeutic applications.
Chemical Information
| Catalog Num | A61630 |
|---|---|
| M. Wt | 629.27 |
| Formula | C35H53ClN4O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2641595-54-0 |
| Synonyms | MC-4R Agonist 2 |
| SMILES | O=C([C@H]1[C@H](C2=CC=C(C=C2)Cl)CN(C1)C(C)(C)C)N3[C@@H](C[C@@H](C3)N([C@@H]4CC[C@@H](CC4)C)C(C(C)C)=O)C(N5CCOCC5)=O |
Biological Activity
| Description | Bivamelagon is a selective agonist of the melanocortin 4 receptor (MC4R) with an EC50 of 0.562 nM in a luciferase assay and 36.5 nM in a cAMP assay, demonstrating its potent activity. This compound exhibits a Ki value of 65 nM, indicating strong binding affinity to its target. Bivamelagon is valuable for research into metabolic disorders, particularly in the context of obesity and diabetes, providing insights into potential therapeutic applications. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
