Product Data Sheet
SNT-207858 free base
Catalog No. A61639
SNT-207858 free base is a selective melanocortin-4 (MC-4) receptor antagonist that effectively penetrates the blood-brain barrier. With an IC50 of 22 nM for binding and 11 nM for functional inhibition, this compound demonstrates potent activity against the MC-4 receptor. It is a valuable tool for research applications focused on understanding melanocortin signaling pathways and their implications in neurological and metabolic disorders.
Chemical Information
| Catalog Num | A61639 |
|---|---|
| M. Wt | 616.62 |
| Formula | C32H43Cl2N5O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1104662-66-9 |
| Synonyms | |
| SMILES | O=C(N1CCCC1)N[C@H](CC2=CC=C(Cl)C=C2Cl)C(N3CCC(C4=NC=CC=C4OC[C@H](N5CCCC5)CC)CC3)=O |
Biological Activity
| Description | SNT-207858 free base is a selective melanocortin-4 (MC-4) receptor antagonist that effectively penetrates the blood-brain barrier. With an IC50 of 22 nM for binding and 11 nM for functional inhibition, this compound demonstrates potent activity against the MC-4 receptor. It is a valuable tool for research applications focused on understanding melanocortin signaling pathways and their implications in neurological and metabolic disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
