Product Data Sheet
ML-00253764 hydrochloride
Catalog No. A61641
ML-00253764 hydrochloride is a nonpeptidic antagonist of the melanocortin receptor 4 (MC4R), demonstrating a Ki of 0.16 μM and an IC50 of 0.103 μM. This compound effectively penetrates the blood-brain barrier, making it suitable for central nervous system studies. Its antagonistic activity at MC4R suggests potential applications in obesity research and metabolic disorder investigations.
Chemical Information
| Catalog Num | A61641 |
|---|---|
| M. Wt | 413.71 |
| Formula | C18H19BrClFN2O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1706524-94-8 |
| Synonyms | |
| SMILES | FC1=C(CCC2=CC(Br)=CC=C2OC)C(C3=NCCN3)=CC=C1.[H]Cl |
Biological Activity
| Description | ML-00253764 hydrochloride is a nonpeptidic antagonist of the melanocortin receptor 4 (MC4R), demonstrating a Ki of 0.16 μM and an IC50 of 0.103 μM. This compound effectively penetrates the blood-brain barrier, making it suitable for central nervous system studies. Its antagonistic activity at MC4R suggests potential applications in obesity research and metabolic disorder investigations. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
