Product Data Sheet
RO27-3225 TFA
Catalog No. A61643
RO27-3225 TFA is a selective agonist of the melanocortin 4 receptor (MC4R), exhibiting an EC50 of 1 nM for MC4R and 8 nM for MC1R, demonstrating approximately 30-fold selectivity for MC4R over MC3R. This compound is recognized for its neuroprotective and anti-inflammatory properties, making it valuable in research related to metabolic regulation and inflammatory conditions. RO27-3225 TFA is suitable for studies focused on the role of MC4R in various physiological and pathological processes.
Chemical Information
| Catalog Num | A61643 |
|---|---|
| M. Wt | 784.91 (free base) |
| Formula | C39H52N12O6.xC2HF3O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1373926-49-8 |
| Synonyms | |
| SMILES | OC(=O)C(F)(F)F.CCCC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N(C)CC(N)=O |
Biological Activity
| Description | RO27-3225 TFA is a selective agonist of the melanocortin 4 receptor (MC4R), exhibiting an EC50 of 1 nM for MC4R and 8 nM for MC1R, demonstrating approximately 30-fold selectivity for MC4R over MC3R. This compound is recognized for its neuroprotective and anti-inflammatory properties, making it valuable in research related to metabolic regulation and inflammatory conditions. RO27-3225 TFA is suitable for studies focused on the role of MC4R in various physiological and pathological processes. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
