Product Data Sheet
GPS1573
Catalog No. A61644
GPS1573 is a noncompetitive antagonist of the melanocortin type 2 receptor (MC2R), exhibiting dose-dependent inhibition of adrenocorticotropic hormone (ACTH)-induced MC2R activity with an IC50 value of 66 nM. This compound is particularly valuable in research focused on Cushing's disease, given its high selectivity for MC2R antagonism. Its properties make GPS1573 an important tool for studying adrenal regulation and related endocrine disorders.
Chemical Information
| Catalog Num | A61644 |
|---|---|
| M. Wt | 1788.20 |
| Formula | C86H138N28O14 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2445822-54-6 |
| Synonyms | |
| SMILES | C([C@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(N)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCCN)=O)=O)C(C)C)=O)C)=O)CCCCN)=O)=O)NC([C@@H](NC([C@H](NC(=O)[C@H]2N(C([C@H](CCCC)N)=O)CCC2)CC3=CC=CC=C3)=O)CCCNC(=N)N)=O)C=4C=5C(NC4)=CC=CC5 |
Biological Activity
| Description | GPS1573 is a noncompetitive antagonist of the melanocortin type 2 receptor (MC2R), exhibiting dose-dependent inhibition of adrenocorticotropic hormone (ACTH)-induced MC2R activity with an IC50 value of 66 nM. This compound is particularly valuable in research focused on Cushing's disease, given its high selectivity for MC2R antagonism. Its properties make GPS1573 an important tool for studying adrenal regulation and related endocrine disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
