Product Data Sheet

γ1-MSH

Catalog No. A61645

main product photo
γ1-MSH is an agonist of the melanocortin MC3 receptor, exhibiting a Ki of 34 nM for the rat MC3 receptor. This compound demonstrates approximately 40-fold selectivity over the MC4 receptor, with a Ki of 1318 nM. γ1-MSH is valuable for research applications exploring the role of melanocortin receptors in metabolic processes and neuroendocrine regulation.
Chemical Information
Catalog NumA61645
M. Wt1512.74
FormulaC72H97N21O14S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.72629-65-3
Synonyms
SMILESC([C@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@H](CC2=CN=CN2)NC(CNC([C@@H](NC([C@@H](NC([C@H](CC3=CC=C(O)C=C3)N)=O)[C@@H](C)C)=O)CCSC)=O)=O)=O)=O)CCCNC(=N)N)=O)C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(N)=O)=O)CCCNC(=N)N)=O)CC(O)=O)=O)C=5C=6C(NC5)=CC=CC6
Biological Activity
Descriptionγ1-MSH is an agonist of the melanocortin MC3 receptor, exhibiting a Ki of 34 nM for the rat MC3 receptor. This compound demonstrates approximately 40-fold selectivity over the MC4 receptor, with a Ki of 1318 nM. γ1-MSH is valuable for research applications exploring the role of melanocortin receptors in metabolic processes and neuroendocrine regulation.
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