Product Data Sheet
[D-Trp8]-γ-MSH
Catalog No. A61651
[D-Trp8]-γ-MSH is a selective agonist of the melanocortin 3 (MC3) receptor, exhibiting an IC50 of 6.7 nM in CHO cells. This compound also demonstrates activity against the MC4 and MC5 receptors, with IC50 values of 600 nM and 340 nM, respectively. [D-Trp8]-γ-MSH is implicated in research applications related to inflammatory disorders, showing potential neuroprotective effects in conditions such as rheumatoid arthritis and colitis.
Chemical Information
| Catalog Num | A61651 |
|---|---|
| M. Wt | 1570.77 |
| Formula | C74H99N21O16S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 321351-81-9 |
| Synonyms | |
| SMILES | C([C@@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@H](CC2=CN=CN2)NC(CNC([C@@H](NC([C@@H](NC([C@H](CC3=CC=C(O)C=C3)N)=O)C(C)C)=O)CCSC)=O)=O)=O)=O)CCCNC(=N)N)=O)C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(NCC(O)=O)=O)=O)CCCNC(=N)N)=O)CC(O)=O)=O)C=5C=6C(NC5)=CC=CC6 |
Biological Activity
| Description | [D-Trp8]-γ-MSH is a selective agonist of the melanocortin 3 (MC3) receptor, exhibiting an IC50 of 6.7 nM in CHO cells. This compound also demonstrates activity against the MC4 and MC5 receptors, with IC50 values of 600 nM and 340 nM, respectively. [D-Trp8]-γ-MSH is implicated in research applications related to inflammatory disorders, showing potential neuroprotective effects in conditions such as rheumatoid arthritis and colitis. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
