Product Data Sheet
Setmelanotide monoacetate
Catalog No. A61658
Setmelanotide monoacetate is a potent agonist of the melanocortin 4 receptor (MC4R), exhibiting EC50 values of 0.27 nM in human and 0.28 nM in rat models. This compound plays a crucial role in regulating appetite and energy homeostasis, making it valuable for research applications related to obesity and metabolic disorders. Its specificity for MC4R also makes it a useful tool for studying melanocortin signaling pathways.
Chemical Information
| Catalog Num | A61658 |
|---|---|
| M. Wt | 1177.36 |
| Formula | C51H72N18O11S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2759937-80-7 |
| Synonyms | RM-493 monoacetate; BIM-22493 monoacetate; IRC-022493 monoacetate |
| SMILES | O=C([C@@H](NC([C@H](NC([C@@H](NC([C@H](NC([C@H](CSSC[C@H](NC1=O)C(N)=O)NC([C@@H](NC(C)=O)CCCNC(N)=N)=O)=O)C)=O)CC2=CN=CN2)=O)CC3=CC=CC=C3)=O)CCCNC(N)=N)N[C@H]1CC4=CNC5=CC=CC=C45.CC(O)=O |
Biological Activity
| Description | Setmelanotide monoacetate is a potent agonist of the melanocortin 4 receptor (MC4R), exhibiting EC50 values of 0.27 nM in human and 0.28 nM in rat models. This compound plays a crucial role in regulating appetite and energy homeostasis, making it valuable for research applications related to obesity and metabolic disorders. Its specificity for MC4R also makes it a useful tool for studying melanocortin signaling pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
