Product Data Sheet
PG-931
Catalog No. A61659
PG-931 is a potent agonist of the melanocortin 4 receptor (MC4R), exhibiting an IC50 of 0.58 nM, while demonstrating selective activity against the human MC3R and MC5R with IC50 values of 55 nM and 2.4 nM, respectively. This compound has shown significant biological activity in reversing haemorrhagic shock and mitigating multiple organ damage in vivo. PG-931 is valuable for research applications focused on obesity, metabolic disorders, and neurodegenerative diseases involving melanocortin signaling pathways.
Chemical Information
| Catalog Num | A61659 |
|---|---|
| M. Wt | 1180.40 |
| Formula | C59H85N15O11 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 667430-81-1 |
| Synonyms | |
| SMILES | C(C=1C=2C(NC1)=CC=CC2)[C@H]3C(=O)N[C@H](C(=O)N4[C@H](C(N[C@@H]([C@@H](C)C)C(N)=O)=O)CCC4)CCCCNC(=O)C[C@H](NC([C@H](CCCC)NC(C)=O)=O)C(=O)N5[C@](C(=O)N[C@H](CC6=CC=CC=C6)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N3)(CCC5)[H] |
Biological Activity
| Description | PG-931 is a potent agonist of the melanocortin 4 receptor (MC4R), exhibiting an IC50 of 0.58 nM, while demonstrating selective activity against the human MC3R and MC5R with IC50 values of 55 nM and 2.4 nM, respectively. This compound has shown significant biological activity in reversing haemorrhagic shock and mitigating multiple organ damage in vivo. PG-931 is valuable for research applications focused on obesity, metabolic disorders, and neurodegenerative diseases involving melanocortin signaling pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
