Product Data Sheet

(-)-Isodocarpin

Catalog No. A61663

main product photo
(-)-Isodocarpin is a diterpenoid that acts as a potent melanogenesis inhibitor, exhibiting an IC50 of 0.19 μM in B16 4A5 cell lines. This compound effectively suppresses the expression of key melanogenic enzymes, including tyrosinase, tyrosine-related protein (TRP)-1, and TRP-2 mRNA. (-)-Isodocarpin is valuable for research applications focused on skin pigmentation, melanin synthesis, and related dermatological studies.
Chemical Information
Catalog NumA61663
M. Wt346.42
FormulaC20H26O5
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.10391-08-9
SynonymsIsodocarpin
SMILESO[C@H]1[C@@]2([H])[C@]3(CO1)[C@@]4([H])[C@@]5(C(O[C@@]3([H])CCC2(C)C)=O)C[C@@](C(C5=O)=C)([H])CC4
Biological Activity
Description(-)-Isodocarpin is a diterpenoid that acts as a potent melanogenesis inhibitor, exhibiting an IC50 of 0.19 μM in B16 4A5 cell lines. This compound effectively suppresses the expression of key melanogenic enzymes, including tyrosinase, tyrosine-related protein (TRP)-1, and TRP-2 mRNA. (-)-Isodocarpin is valuable for research applications focused on skin pigmentation, melanin synthesis, and related dermatological studies.
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