Product Data Sheet
PG106
Catalog No. A61678
PG106 is a selective antagonist of the human melanocortin 3 (hMC3) receptor, exhibiting a potency with an IC50 of 210 nM. The compound demonstrates significant specificity, showing minimal activity at the hMC4 receptor (EC50 of 9900 nM) and no interaction with the hMC5 receptor. Research applications include studies focused on metabolic regulation and potential therapeutic targets related to obesity and related disorders.
Chemical Information
| Catalog Num | A61678 |
|---|---|
| M. Wt | 1008.18 |
| Formula | C51H69N13O9 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 944111-22-2 |
| Synonyms | |
| SMILES | C(C=1C=2C(NC1)=CC=CC2)[C@@H]3NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](CC4=CC5=C(C=C4)C=CC=C5)NC(=O)CCNC(=O)[C@@H](NC([C@H](CCCC)NC(C)=O)=O)CC(=O)NCCCC[C@@H](C(N)=O)NC3=O |
Biological Activity
| Description | PG106 is a selective antagonist of the human melanocortin 3 (hMC3) receptor, exhibiting a potency with an IC50 of 210 nM. The compound demonstrates significant specificity, showing minimal activity at the hMC4 receptor (EC50 of 9900 nM) and no interaction with the hMC5 receptor. Research applications include studies focused on metabolic regulation and potential therapeutic targets related to obesity and related disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
