Product Data Sheet

ACTH (1-17)

Catalog No. A61698

main product photo
ACTH (1-17) is a potent agonist of the human melanocortin 1 (MC1) receptor, exhibiting a Ki of 0.21 nM. This adrenocorticotropin analogue plays a critical role in modulating melanogenesis and has significant implications for research in skin pigmentation and endocrine regulation. Its efficacy makes it a valuable tool for studies focused on melanocortin signaling pathways and related therapeutic applications.
Chemical Information
Catalog NumA61698
M. Wt2093.41
FormulaC95H145N29O23S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.7266-47-9
Synonymsα1-17-ACTH
SMILESCSCCC(NC(=O)C(CO)NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(N)CO)C(=O)NC(CCC(O)=O)C(=O)NC(Cc1c[nH]cn1)C(=O)NC(Cc1ccccc1)C(=O)NC(CCCNC(N)=N)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCC(=O)NC(CCCCN)C(=O)N1CCCC1C(=O)NC(C(C)C)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCNC(N)=N)C(O)=O
Biological Activity
DescriptionACTH (1-17) is a potent agonist of the human melanocortin 1 (MC1) receptor, exhibiting a Ki of 0.21 nM. This adrenocorticotropin analogue plays a critical role in modulating melanogenesis and has significant implications for research in skin pigmentation and endocrine regulation. Its efficacy makes it a valuable tool for studies focused on melanocortin signaling pathways and related therapeutic applications.
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