S26131
Catalog No. A61717

S26131 is a potent and selective antagonist of the MT1 melatonin receptor, exhibiting Ki values of 0.5 nM for MT1 and 112 nM for MT2. This compound's affinity and selectivity make it a valuable tool for studying melatonergic signaling pathways and their implications in various physiological and pathological processes. S26131 can be utilized in research exploring sleep regulation, circadian rhythms, and related neurobiological functions.
Chemical Information
| Catalog Num | A61717 |
|---|---|
| M. Wt | 498.61 |
| Formula | C31H34N2O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 296280-56-3 |
| Synonyms | |
| SMILES | CC(NCCC1=C2C=C(C=CC2=CC=C1)OCCCOC3=CC=C4C=CC=C(C4=C3)CCNC(C)=O)=O |
Biological Activity
| Description | S26131 is a potent and selective antagonist of the MT1 melatonin receptor, exhibiting Ki values of 0.5 nM for MT1 and 112 nM for MT2. This compound's affinity and selectivity make it a valuable tool for studying melatonergic signaling pathways and their implications in various physiological and pathological processes. S26131 can be utilized in research exploring sleep regulation, circadian rhythms, and related neurobiological functions. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


