Product Data Sheet
8-M-PDOT
Catalog No. A61719
8-M-PDOT is a selective agonist for the melatonin MT2 receptor, displaying a 5.2-fold preference for MT2 over MT1 receptors. It exhibits high binding affinity with human recombinant MT2 and MT1 receptors, demonstrating pKi values of 8.23 and 8.95, respectively. This compound exhibits anxiolytic-like properties, making it a valuable tool for research in sleep disorders and anxiety-related studies.
Chemical Information
| Catalog Num | A61719 |
|---|---|
| M. Wt | 233.31 |
| Formula | C14H19NO2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 134865-70-6 |
| Synonyms | AH-002 |
| SMILES | CCC(NC1CC2=C(C=CC=C2OC)CC1)=O |
Biological Activity
| Description | 8-M-PDOT is a selective agonist for the melatonin MT2 receptor, displaying a 5.2-fold preference for MT2 over MT1 receptors. It exhibits high binding affinity with human recombinant MT2 and MT1 receptors, demonstrating pKi values of 8.23 and 8.95, respectively. This compound exhibits anxiolytic-like properties, making it a valuable tool for research in sleep disorders and anxiety-related studies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
