Product Data Sheet
Ramelteon-d5
Catalog No. A61724
Ramelteon-d5 is a deuterated form of Ramelteon, a highly selective and potent agonist of the MT1 and MT2 melatonin receptors, exhibiting Ki values of 14 pM and 112 pM, respectively. This stable isotope is valuable for research studies focusing on insomnia and sleep disorders, as Ramelteon has demonstrated efficacy in reducing sleep onset during long-term treatment without leading to next-morning residual effects or withdrawal symptoms upon discontinuation. Researchers can utilize Ramelteon-d5 in pharmacokinetic and metabolic studies to gain insights into the compound's mechanism and therapeutic potential.
Chemical Information
| Catalog Num | A61724 |
|---|---|
| M. Wt | 264.37 |
| Formula | C16H16D5NO2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1134159-63-9 |
| Synonyms | TAK-375-d5 |
| SMILES | [2H]C([2H])([2H])C([2H])([2H])C(NCC[C@H]1C2=C(CC1)C=CC3=C2CCO3)=O |
Biological Activity
| Description | Ramelteon-d5 is a deuterated form of Ramelteon, a highly selective and potent agonist of the MT1 and MT2 melatonin receptors, exhibiting Ki values of 14 pM and 112 pM, respectively. This stable isotope is valuable for research studies focusing on insomnia and sleep disorders, as Ramelteon has demonstrated efficacy in reducing sleep onset during long-term treatment without leading to next-morning residual effects or withdrawal symptoms upon discontinuation. Researchers can utilize Ramelteon-d5 in pharmacokinetic and metabolic studies to gain insights into the compound's mechanism and therapeutic potential. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
