Product Data Sheet
N-Pentanoyl 2-benzyltryptamine
Catalog No. A61726
N-Pentanoyl 2-benzyltryptamine is a selective antagonist of the MT2 melatonin receptor, exhibiting a pKi of 8.03 for human MT2. This compound demonstrates significant selectivity, with 89-fold and 229-fold preference for human MT2 over human MT1 and Xenopus mel1c receptor subtypes, respectively. N-Pentanoyl 2-benzyltryptamine effectively inhibits melatonin-induced enhancement of electrically-evoked responses, making it a valuable tool for research in circadian rhythms and melatonin signaling pathways.
Chemical Information
| Catalog Num | A61726 |
|---|---|
| M. Wt | 334.45 |
| Formula | C22H26N2O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 220339-00-4 |
| Synonyms | |
| SMILES | CCCCC(NCCC1=C(CC2=CC=CC=C2)NC3=C1C=CC=C3)=O |
Biological Activity
| Description | N-Pentanoyl 2-benzyltryptamine is a selective antagonist of the MT2 melatonin receptor, exhibiting a pKi of 8.03 for human MT2. This compound demonstrates significant selectivity, with 89-fold and 229-fold preference for human MT2 over human MT1 and Xenopus mel1c receptor subtypes, respectively. N-Pentanoyl 2-benzyltryptamine effectively inhibits melatonin-induced enhancement of electrically-evoked responses, making it a valuable tool for research in circadian rhythms and melatonin signaling pathways. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
