Product Data Sheet
Ramelteon-d3
Catalog No. A61736
Ramelteon-d3 is a deuterium-labeled derivative of Ramelteon, a highly selective and orally active agonist of melatonin receptors MT1 and MT2, exhibiting Ki values of 14 pM and 112 pM, respectively. This stable isotope is utilized in pharmacokinetic studies and research applications focused on insomnia, providing insight into sleep modulation mechanisms. Ramelteon is known for its efficacy in reducing sleep onset without causing residual effects, rebound insomnia, or withdrawal symptoms with long-term use.
Chemical Information
| Catalog Num | A61736 |
|---|---|
| M. Wt | 262.36 |
| Formula | C16H18D3NO2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1432057-38-9 |
| Synonyms | TAK-375-d3 |
| SMILES | [2H]C([2H])([2H])CC(NCC[C@H]1C2=C(CC1)C=CC3=C2CCO3)=O |
Biological Activity
| Description | Ramelteon-d3 is a deuterium-labeled derivative of Ramelteon, a highly selective and orally active agonist of melatonin receptors MT1 and MT2, exhibiting Ki values of 14 pM and 112 pM, respectively. This stable isotope is utilized in pharmacokinetic studies and research applications focused on insomnia, providing insight into sleep modulation mechanisms. Ramelteon is known for its efficacy in reducing sleep onset without causing residual effects, rebound insomnia, or withdrawal symptoms with long-term use. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
