Product Data Sheet

VU0477573

Catalog No. A61740

main product photo
VU0477573, a partial negative allosteric modulator of metabotropic glutamate receptor subtype 5 (mGluR5), demonstrates brain penetrance and engages in neuroprotective and anxiolytic activities. This compound is of significant interest in the research of neurological disorders, including Parkinson's disease, providing insights into potential therapeutic strategies targeting mGluR5.
Chemical Information
Catalog NumA61740
M. Wt296.34
FormulaC18H17FN2O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1946021-40-4
Synonyms
SMILESO=C(N(CC)CC)C1=NC=C(C=C1)C#CC2=CC(F)=CC=C2
Biological Activity
DescriptionVU0477573, a partial negative allosteric modulator of metabotropic glutamate receptor subtype 5 (mGluR5), demonstrates brain penetrance and engages in neuroprotective and anxiolytic activities. This compound is of significant interest in the research of neurological disorders, including Parkinson's disease, providing insights into potential therapeutic strategies targeting mGluR5.
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