Product Data Sheet
AMN082
Catalog No. A61748
AMN082 is a selective mGluR7 agonist that operates through allosteric activation of the receptor signaling pathway. It effectively inhibits cAMP accumulation and promotes GTPγS binding in transfected mammalian cells, with EC50 values ranging from 64 to 290 nM. AMN082 demonstrates notable selectivity for mGluR7 over other mGluR subtypes and ionotropic glutamate receptors, making it a valuable tool for research into neuropharmacology and potential antidepressant effects.
Chemical Information
| Catalog Num | A61748 |
|---|---|
| M. Wt | 465.46 |
| Formula | C28H30Cl2N2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 97075-46-2 |
| Synonyms | |
| SMILES | [H]Cl.[H]Cl.C(NCCNC(C1=CC=CC=C1)C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4 |
Biological Activity
| Description | AMN082 is a selective mGluR7 agonist that operates through allosteric activation of the receptor signaling pathway. It effectively inhibits cAMP accumulation and promotes GTPγS binding in transfected mammalian cells, with EC50 values ranging from 64 to 290 nM. AMN082 demonstrates notable selectivity for mGluR7 over other mGluR subtypes and ionotropic glutamate receptors, making it a valuable tool for research into neuropharmacology and potential antidepressant effects. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
