Product Data Sheet

VU6010572

Catalog No. A61751

main product photo
VU6010572 is a potent and selective negative allosteric modulator of the metabotropic glutamate receptor 3 (mGlu3), demonstrating an IC50 of 245 nM. Its high blood-brain barrier penetration makes it suitable for central nervous system studies. This compound is valuable in investigating the role of mGlu3 in neuropsychiatric disorders and evaluating potential therapeutic strategies in related research contexts.
Chemical Information
Catalog NumA61751
M. Wt339.36
FormulaC20H18FNO3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2126784-39-0
Synonyms
SMILESO=C1C=C(OC[C@@H](OC2=CC=CC=C2)C)C=CN1C3=CC=C(F)C=C3
Biological Activity
DescriptionVU6010572 is a potent and selective negative allosteric modulator of the metabotropic glutamate receptor 3 (mGlu3), demonstrating an IC50 of 245 nM. Its high blood-brain barrier penetration makes it suitable for central nervous system studies. This compound is valuable in investigating the role of mGlu3 in neuropsychiatric disorders and evaluating potential therapeutic strategies in related research contexts.
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