XAP044
Catalog No. A61764

XAP044 is a highly selective antagonist of the metabotropic glutamate receptor subtype 7 (mGlu7), which serves as a key presynaptic modulator of neurotransmission in the central nervous system. It is characterized by significant brain permeability and has been shown to exhibit a broad range of anti-stress effects, as well as antidepressant and anxiolytic-like activity in rodent behavioral models. This compound is useful for research applications aimed at understanding mGlu7's role in neuropsychiatric disorders.
Chemical Information
| Catalog Num | A61764 |
|---|---|
| M. Wt | 380.13 |
| Formula | C15H9IO4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 196928-50-4 |
| Synonyms | |
| SMILES | O=C1C2=CC=C(O)C=C2OC=C1OC3=CC=C(I)C=C3 |
Biological Activity
| Description | XAP044 is a highly selective antagonist of the metabotropic glutamate receptor subtype 7 (mGlu7), which serves as a key presynaptic modulator of neurotransmission in the central nervous system. It is characterized by significant brain permeability and has been shown to exhibit a broad range of anti-stress effects, as well as antidepressant and anxiolytic-like activity in rodent behavioral models. This compound is useful for research applications aimed at understanding mGlu7's role in neuropsychiatric disorders. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


