Product Data Sheet

mGluR2 modulator 1

Catalog No. A61765

main product photo
mGluR2 modulator 1 is a potent positive allosteric modulator of the metabotropic glutamate receptor-2 (mGluR2), exhibiting an EC50 of 0.03 μM and effective blood-brain barrier penetration. This compound is valuable for investigating the role of mGluR2 in neuropsychiatric disorders, particularly in psychosis research, where modulation of glutamatergic signaling may provide therapeutic insights.
Chemical Information
Catalog NumA61765
M. Wt419.40
FormulaC21H20F3N3O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2671063-84-4
Synonyms
SMILESO=C1N(CCN2C1=NC3=C2C=CC=C3)CCCCOC4=CC=C(C=C4)OC(F)(F)F
Biological Activity
DescriptionmGluR2 modulator 1 is a potent positive allosteric modulator of the metabotropic glutamate receptor-2 (mGluR2), exhibiting an EC50 of 0.03 μM and effective blood-brain barrier penetration. This compound is valuable for investigating the role of mGluR2 in neuropsychiatric disorders, particularly in psychosis research, where modulation of glutamatergic signaling may provide therapeutic insights.
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SHIPPING AND STORAGE
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