Product Data Sheet
VU6043653
Catalog No. A61777
VU6043653 is a potent negative allosteric modulator of the metabotropic glutamate receptor subtype 5 (mGlu5), exhibiting an IC50 value of 325 nM for human mGlu5. This compound selectively influences mGlu5 signaling pathways, making it a valuable tool for studying neuropharmacology and neurodegenerative diseases. Its ability to cross the blood-brain barrier enhances its utility in in vivo research applications focused on central nervous system disorders.
Chemical Information
| Catalog Num | A61777 |
|---|---|
| M. Wt | 327.31 |
| Formula | C16H14FN5O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3032791-06-0 |
| Synonyms | |
| SMILES | CC1=NC(C(NC2=CC=C(F)C=N2)=O)=CC(OC3=CN(C)N=C3)=C1 |
Biological Activity
| Description | VU6043653 is a potent negative allosteric modulator of the metabotropic glutamate receptor subtype 5 (mGlu5), exhibiting an IC50 value of 325 nM for human mGlu5. This compound selectively influences mGlu5 signaling pathways, making it a valuable tool for studying neuropharmacology and neurodegenerative diseases. Its ability to cross the blood-brain barrier enhances its utility in in vivo research applications focused on central nervous system disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
