Product Data Sheet

CBiPES

Catalog No. A61779

main product photo
CBiPES is a potent positive allosteric modulator of the mGlu2 receptor, exhibiting an EC50 of 92.8 nM. This compound effectively attenuates stress-induced hyperthermia and phencyclidine-induced hyperlocomotor activity, making it a valuable tool in the study of neurological disorders. CBiPES is particularly relevant for research related to Parkinson's disease and other neuropsychiatric conditions.
Chemical Information
Catalog NumA61779
M. Wt377.46
FormulaC21H19N3O2S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.353235-01-5
Synonyms
SMILESCCS(N(C1=CC(C2=CC=C(C#N)C=C2)=CC=C1)CC3=CN=CC=C3)(=O)=O
Biological Activity
DescriptionCBiPES is a potent positive allosteric modulator of the mGlu2 receptor, exhibiting an EC50 of 92.8 nM. This compound effectively attenuates stress-induced hyperthermia and phencyclidine-induced hyperlocomotor activity, making it a valuable tool in the study of neurological disorders. CBiPES is particularly relevant for research related to Parkinson's disease and other neuropsychiatric conditions.
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