Product Data Sheet

UPF-523

Catalog No. A61785

main product photo
UPF-523 is a selective antagonist of the group I metabotropic glutamate receptor mGlu1a, exhibiting a potency with an IC50 of 214 µM. This compound does not influence group II (mGlu2), group III (mGlu4), or ionotropic glutamate receptors. UPF-523 serves as a valuable tool in research related to acute arthritis, facilitating the investigation of therapeutic strategies targeting mGlu1a receptor pathways.
Chemical Information
Catalog NumA61785
M. Wt221.21
FormulaC11H11NO4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.168560-79-0
SynonymsAIDA
SMILESO=C(C1(N)CCC2=C1C=CC(C(O)=O)=C2)O
Biological Activity
DescriptionUPF-523 is a selective antagonist of the group I metabotropic glutamate receptor mGlu1a, exhibiting a potency with an IC50 of 214 µM. This compound does not influence group II (mGlu2), group III (mGlu4), or ionotropic glutamate receptors. UPF-523 serves as a valuable tool in research related to acute arthritis, facilitating the investigation of therapeutic strategies targeting mGlu1a receptor pathways.
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