Product Data Sheet
MNI137
Catalog No. A61791
MNI137 is a potent and selective negative allosteric modulator targeting group II metabotropic glutamate receptors (mGluRs). With IC50 values of 8.3 nM for human mGlu2 and 12.6 nM for rat mGlu2, MNI137 effectively inhibits glutamate-induced calcium mobilization. This compound is valuable for research applications in neuropharmacology and the exploration of mGluR-related disorders.
Chemical Information
| Catalog Num | A61791 |
|---|---|
| M. Wt | 341.16 |
| Formula | C15H9BrN4O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 946619-21-2 |
| Synonyms | |
| SMILES | N#CC1=NC=CC(C2=NC3=CC=C(Br)C=C3NC(C2)=O)=C1 |
Biological Activity
| Description | MNI137 is a potent and selective negative allosteric modulator targeting group II metabotropic glutamate receptors (mGluRs). With IC50 values of 8.3 nM for human mGlu2 and 12.6 nM for rat mGlu2, MNI137 effectively inhibits glutamate-induced calcium mobilization. This compound is valuable for research applications in neuropharmacology and the exploration of mGluR-related disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
