Product Data Sheet
(RS)-PPG
Catalog No. A61794
(RS)-PPG is a selective agonist for group III metabotropic glutamate receptors (mGluRs), exhibiting potent activity with EC50 values of 5.2 μM for hmGluR4a, 4.7 μM for hmGluR6, 185 μM for hmGluR7b, and 0.2 μM for hmGluR8a. This compound demonstrates significant anticonvulsive and neuroprotective effects, making it a valuable tool in neurological research. Its ability to modulate mGluR activity positions (RS)-PPG for potential applications in studying various neuropsychiatric disorders.
Chemical Information
| Catalog Num | A61794 |
|---|---|
| M. Wt | 231.14 |
| Formula | C8H10NO5P |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 120667-15-4 |
| Synonyms | |
| SMILES | O=C(O)C(N)C1=CC=C(P(O)(O)=O)C=C1 |
Biological Activity
| Description | (RS)-PPG is a selective agonist for group III metabotropic glutamate receptors (mGluRs), exhibiting potent activity with EC50 values of 5.2 μM for hmGluR4a, 4.7 μM for hmGluR6, 185 μM for hmGluR7b, and 0.2 μM for hmGluR8a. This compound demonstrates significant anticonvulsive and neuroprotective effects, making it a valuable tool in neurological research. Its ability to modulate mGluR activity positions (RS)-PPG for potential applications in studying various neuropsychiatric disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
