Product Data Sheet
AMN082 free base
Catalog No. A61798
AMN082 free base is a selective mGluR7 agonist that activates receptor signaling through an allosteric site within the transmembrane domain. This compound effectively inhibits cAMP accumulation and promotes GTPγS binding at transfected mammalian cells expressing mGluR7, with EC50 values ranging from 64 to 290 nM. AMN082 free base demonstrates selectivity for mGluR7 over other metabotropic glutamate receptor subtypes and certain ionotropic glutamate receptors, highlighting its potential for research in neuroscience and depression-related studies.
Chemical Information
| Catalog Num | A61798 |
|---|---|
| M. Wt | 392.54 |
| Formula | C28H28N2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 83027-13-8 |
| Synonyms | |
| SMILES | C(C1=CC=CC=C1)(C2=CC=CC=C2)NCCNC(C3=CC=CC=C3)C4=CC=CC=C4 |
Biological Activity
| Description | AMN082 free base is a selective mGluR7 agonist that activates receptor signaling through an allosteric site within the transmembrane domain. This compound effectively inhibits cAMP accumulation and promotes GTPγS binding at transfected mammalian cells expressing mGluR7, with EC50 values ranging from 64 to 290 nM. AMN082 free base demonstrates selectivity for mGluR7 over other metabotropic glutamate receptor subtypes and certain ionotropic glutamate receptors, highlighting its potential for research in neuroscience and depression-related studies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
