Product Data Sheet
Valiglurax
Catalog No. A61802
Valiglurax is a potent, orally active positive allosteric modulator of the metabotropic glutamate receptor 4 (mGlu4), exhibiting EC50 values of 64.6 nM and 197 nM for human mGlu4/Gqi5 and rat mGlu4 GIRK, respectively. It effectively penetrates the central nervous system (CNS), making it a valuable tool for studying pharmacological pathways involved in neurological disorders. Valiglurax is particularly relevant for research focused on Parkinson's disease, enabling investigations into potential therapeutic interventions.
Chemical Information
| Catalog Num | A61802 |
|---|---|
| M. Wt | 329.28 |
| Formula | C16H10F3N5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1976050-09-5 |
| Synonyms | VU0652957; VU2957 |
| SMILES | FC(C1=NC=CC2=C1C=CC(NC3=NNC4=NC=CC=C43)=C2)(F)F |
Biological Activity
| Description | Valiglurax is a potent, orally active positive allosteric modulator of the metabotropic glutamate receptor 4 (mGlu4), exhibiting EC50 values of 64.6 nM and 197 nM for human mGlu4/Gqi5 and rat mGlu4 GIRK, respectively. It effectively penetrates the central nervous system (CNS), making it a valuable tool for studying pharmacological pathways involved in neurological disorders. Valiglurax is particularly relevant for research focused on Parkinson's disease, enabling investigations into potential therapeutic interventions. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
