Product Data Sheet
TASP0433864
Catalog No. A61807
TASP0433864 is a selective positive allosteric modulator (PAM) of the metabotropic glutamate 2 (mGlu2) receptor, exhibiting EC50 values of 199 nM and 206 nM for human and rat mGlu2 receptors, respectively. This compound demonstrates significant antipsychotic activity, making it a valuable tool for research into neuropsychiatric disorders. Its ability to modulate mGlu2 receptor activity highlights its potential in studying glutamatergic signaling and developing new therapeutics for related conditions.
Chemical Information
| Catalog Num | A61807 |
|---|---|
| M. Wt | 329.39 |
| Formula | C18H23N3O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1431980-60-7 |
| Synonyms | |
| SMILES | O=C(C1=C(C)N2C(O[C@H](COC3=CC=C(C(C)(C)C)C=C3)C2)=N1)N |
Biological Activity
| Description | TASP0433864 is a selective positive allosteric modulator (PAM) of the metabotropic glutamate 2 (mGlu2) receptor, exhibiting EC50 values of 199 nM and 206 nM for human and rat mGlu2 receptors, respectively. This compound demonstrates significant antipsychotic activity, making it a valuable tool for research into neuropsychiatric disorders. Its ability to modulate mGlu2 receptor activity highlights its potential in studying glutamatergic signaling and developing new therapeutics for related conditions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
