Product Data Sheet

VU0285683

Catalog No. A61808

main product photo
VU0285683 is a selective positive allosteric modulator (PAM) of the metabotropic glutamate receptor 5 (mGluR5). It demonstrates anxiolytic-like effects in rodent models of anxiety, providing valuable insights into the modulation of glutamatergic signaling. This compound is primarily utilized in biological research focused on anxiety disorders and the pharmacological mechanisms underlying mGluR5 modulation.
Chemical Information
Catalog NumA61808
M. Wt266.23
FormulaC14H7FN4O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.327056-22-4
Synonyms
SMILESN#CC1=CC(C2=NC(C3=NC=CC=C3)=NO2)=CC(F)=C1
Biological Activity
DescriptionVU0285683 is a selective positive allosteric modulator (PAM) of the metabotropic glutamate receptor 5 (mGluR5). It demonstrates anxiolytic-like effects in rodent models of anxiety, providing valuable insights into the modulation of glutamatergic signaling. This compound is primarily utilized in biological research focused on anxiety disorders and the pharmacological mechanisms underlying mGluR5 modulation.
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