Product Data Sheet
LY367385
Catalog No. A61810
LY367385 is a highly selective antagonist of the metabotropic glutamate receptor 1a (mGluR1a). This compound demonstrates an IC50 of 8.8 μM in inhibiting quisqualate-induced phosphoinositide hydrolysis, showcasing its potency in modulating mGluR1a activity. LY367385 has been investigated for its neuroprotective, anticonvulsant, and antiepileptic effects, making it a valuable reagent for research in neuropharmacology and epilepsy studies.
Chemical Information
| Catalog Num | A61810 |
|---|---|
| M. Wt | 209.20 |
| Formula | C10H11NO4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 198419-91-9 |
| Synonyms | |
| SMILES | OC([C@H](C1=C(C=C(C(O)=O)C=C1)C)N)=O |
Biological Activity
| Description | LY367385 is a highly selective antagonist of the metabotropic glutamate receptor 1a (mGluR1a). This compound demonstrates an IC50 of 8.8 μM in inhibiting quisqualate-induced phosphoinositide hydrolysis, showcasing its potency in modulating mGluR1a activity. LY367385 has been investigated for its neuroprotective, anticonvulsant, and antiepileptic effects, making it a valuable reagent for research in neuropharmacology and epilepsy studies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
