Product Data Sheet
VU-1545
Catalog No. A61813
VU-1545 is a positive allosteric modulator of metabotropic glutamate receptor 5 (mGluR5) with a Ki of 156 nM and an EC50 of 9.6 nM. This compound enhances mGluR5 activity, offering potential insights into synaptic transmission and plasticity. VU-1545 is valuable in research focused on neurological disorders, cognition, and mood regulation, making it a useful tool for studying the role of mGluR5 in various pathological conditions.
Chemical Information
| Catalog Num | A61813 |
|---|---|
| M. Wt | 402.38 |
| Formula | C22H15FN4O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 890764-63-3 |
| Synonyms | |
| SMILES | O=C(NC1=CC(C2=CC=CC=C2)=NN1C3=CC=CC=C3F)C4=CC=C([N+]([O-])=O)C=C4 |
Biological Activity
| Description | VU-1545 is a positive allosteric modulator of metabotropic glutamate receptor 5 (mGluR5) with a Ki of 156 nM and an EC50 of 9.6 nM. This compound enhances mGluR5 activity, offering potential insights into synaptic transmission and plasticity. VU-1545 is valuable in research focused on neurological disorders, cognition, and mood regulation, making it a useful tool for studying the role of mGluR5 in various pathological conditions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
