Product Data Sheet
LY3020371
Catalog No. A61817
LY3020371 is a highly selective antagonist of the metabotropic glutamate receptors 2 and 3 (mGluR2/3), exhibiting inhibition constants (Kis) of 5.26 nM and 2.50 nM for human mGluR2 and mGluR3, respectively. This compound is primarily utilized in research focused on understanding the pathophysiology of depression and exploring potential therapeutic interventions. Its potent activity against these targets makes it a valuable tool for studying the glutamatergic system in neurological disorders.
Chemical Information
| Catalog Num | A61817 |
|---|---|
| M. Wt | 359.35 |
| Formula | C15H15F2NO5S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1377615-75-2 |
| Synonyms | |
| SMILES | O=C([C@@]1(N)[C@]2([H])[C@@H](C(O)=O)[C@]2([H])[C@H](O)[C@H]1CSC3=CC=C(F)C(F)=C3)O |
Biological Activity
| Description | LY3020371 is a highly selective antagonist of the metabotropic glutamate receptors 2 and 3 (mGluR2/3), exhibiting inhibition constants (Kis) of 5.26 nM and 2.50 nM for human mGluR2 and mGluR3, respectively. This compound is primarily utilized in research focused on understanding the pathophysiology of depression and exploring potential therapeutic interventions. Its potent activity against these targets makes it a valuable tool for studying the glutamatergic system in neurological disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
