Raseglurant
Catalog No. A61825

Raseglurant (ADX-10059) is a negative allosteric modulator of the mGlu5 receptor, demonstrating potential therapeutic effects in migraine management. This compound has been shown to alleviate Haloperidol-induced catalepsy in murine models, indicating its utility in studying disorders related to dopaminergic signaling. Raseglurant can be employed in research focused on the modulation of mGlu5 receptor activity and its implications in neurological diseases.
Chemical Information
| Catalog Num | A61825 |
|---|---|
| M. Wt | 240.28 |
| Formula | C15H13FN2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 757950-09-7 |
| Synonyms | ADX-10059 |
| SMILES | NC1=C(C)C=C(C)N=C1C#CC2=CC=CC(F)=C2 |
Biological Activity
| Description | Raseglurant (ADX-10059) is a negative allosteric modulator of the mGlu5 receptor, demonstrating potential therapeutic effects in migraine management. This compound has been shown to alleviate Haloperidol-induced catalepsy in murine models, indicating its utility in studying disorders related to dopaminergic signaling. Raseglurant can be employed in research focused on the modulation of mGlu5 receptor activity and its implications in neurological diseases. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


