Product Data Sheet
LSN2814617
Catalog No. A61837
LSN2814617 is a selective positive allosteric modulator of the metabotropic glutamate receptor 5 (mGlu5), exhibiting potent oral bioactivity with EC50 values of 52 nM in human and 42 nM in rat models. This compound has demonstrated a wake-promoting effect, making it a valuable tool in the investigation of neurological disorders. LSN2814617 is particularly relevant for research focused on schizophrenia and related conditions, where modulation of glutamatergic signaling may provide therapeutic insights.
Chemical Information
| Catalog Num | A61837 |
|---|---|
| M. Wt | 341.38 |
| Formula | C18H20FN5O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1313498-17-7 |
| Synonyms | |
| SMILES | FC1=CC=C(C=C1)C2=NOC([C@@H]3CC4=NN=C(N4CC3)C(C)(C)C)=N2 |
Biological Activity
| Description | LSN2814617 is a selective positive allosteric modulator of the metabotropic glutamate receptor 5 (mGlu5), exhibiting potent oral bioactivity with EC50 values of 52 nM in human and 42 nM in rat models. This compound has demonstrated a wake-promoting effect, making it a valuable tool in the investigation of neurological disorders. LSN2814617 is particularly relevant for research focused on schizophrenia and related conditions, where modulation of glutamatergic signaling may provide therapeutic insights. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
