Product Data Sheet

JNJ-40068782

Catalog No. A61838

main product photo
JNJ-40068782 is a potent positive allosteric modulator of the metabotropic glutamate receptor 2 (mGlu2). With an IC50 value of 38 nM, this compound enhances mGlu2 receptor activity, influencing various neurobiological processes. It is primarily utilized in research investigating neurological disorders and psychiatric conditions, providing insight into mGlu2 signaling pathways and potential therapeutic applications.
Chemical Information
Catalog NumA61838
M. Wt333.43
FormulaC21H23N3O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.950196-50-6
Synonyms
SMILESN#CC1=C(C=CN(C1=O)CC2CC2)N3CCC(CC3)C4=CC=CC=C4
Biological Activity
DescriptionJNJ-40068782 is a potent positive allosteric modulator of the metabotropic glutamate receptor 2 (mGlu2). With an IC50 value of 38 nM, this compound enhances mGlu2 receptor activity, influencing various neurobiological processes. It is primarily utilized in research investigating neurological disorders and psychiatric conditions, providing insight into mGlu2 signaling pathways and potential therapeutic applications.
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