Product Data Sheet
DL-AP4 sodium
Catalog No. A61848
DL-AP4 sodium (2-Amino-4-phosphonobutyric acid sodium) is a potent agonist for metabotropic glutamate receptors (mGluR), specifically targeting mGluR4. This compound activates a signaling pathway that inhibits adenylate cyclase activity, consequently reducing Forskolin-induced cAMP production. Additionally, DL-AP4 sodium functions as an inhibitor of ON channels, leading to decreased sensitivity of photoreceptors to variations in brightness. These properties make it a valuable tool for research in neuropharmacology and synaptic plasticity.
Chemical Information
| Catalog Num | A61848 |
|---|---|
| M. Wt | 205.08 |
| Formula | C4H9NNaO5P |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1263093-79-3 |
| Synonyms | 2-Amino-4-phosphonobutyric acid sodium |
| SMILES | OC(C(N)CCP(O)(O[Na])=O)=O |
Biological Activity
| Description | DL-AP4 sodium (2-Amino-4-phosphonobutyric acid sodium) is a potent agonist for metabotropic glutamate receptors (mGluR), specifically targeting mGluR4. This compound activates a signaling pathway that inhibits adenylate cyclase activity, consequently reducing Forskolin-induced cAMP production. Additionally, DL-AP4 sodium functions as an inhibitor of ON channels, leading to decreased sensitivity of photoreceptors to variations in brightness. These properties make it a valuable tool for research in neuropharmacology and synaptic plasticity. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
