Product Data Sheet
VU0092273
Catalog No. A61856
VU0092273 is a potent positive allosteric modulator (PAM) of the metabotropic glutamate receptor 5 (mGlu5), exhibiting an EC50 value of 0.27 μM. This compound enhances mGlu5 receptor activity by binding to the MPEP site, thereby increasing the responsiveness of the receptor to glutamate. VU0092273 is utilized in research applications investigating synaptic plasticity, neuroprotection, and potential therapeutic strategies for neuropsychiatric disorders.
Chemical Information
| Catalog Num | A61856 |
|---|---|
| M. Wt | 305.37 |
| Formula | C20H19NO2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 393110-43-5 |
| Synonyms | |
| SMILES | O=C(N1CCC(O)CC1)C2=CC=C(C#CC3=CC=CC=C3)C=C2 |
Biological Activity
| Description | VU0092273 is a potent positive allosteric modulator (PAM) of the metabotropic glutamate receptor 5 (mGlu5), exhibiting an EC50 value of 0.27 μM. This compound enhances mGlu5 receptor activity by binding to the MPEP site, thereby increasing the responsiveness of the receptor to glutamate. VU0092273 is utilized in research applications investigating synaptic plasticity, neuroprotection, and potential therapeutic strategies for neuropsychiatric disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
