Product Data Sheet

MTPG

Catalog No. A61869

main product photo
MTPG is a potent antagonist of metabotropic glutamate receptors 2 (mGluR2) and 3 (mGluR3). It effectively blocks the induction of brain ischemic tolerance facilitated by cerebral ischemic preconditioning. Additionally, MTPG significantly reduces the inhibitory effect of L-CCG-1 on potassium chloride (KCl)-induced dopamine release, making it a valuable tool for research in neuropharmacology and cerebrovascular studies.
Chemical Information
Catalog NumA61869
M. Wt233.23
FormulaC10H11N5O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.169209-66-9
Synonyms
SMILESO=C(O)C(C)(N)C1=CC=C(C2=NN=NN2)C=C1
Biological Activity
DescriptionMTPG is a potent antagonist of metabotropic glutamate receptors 2 (mGluR2) and 3 (mGluR3). It effectively blocks the induction of brain ischemic tolerance facilitated by cerebral ischemic preconditioning. Additionally, MTPG significantly reduces the inhibitory effect of L-CCG-1 on potassium chloride (KCl)-induced dopamine release, making it a valuable tool for research in neuropharmacology and cerebrovascular studies.
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