Product Data Sheet

GSK1331268

Catalog No. A61873

main product photo
GSK1331268 is a selective, orally active agonist of the metabotropic glutamate receptor 2 (mGluR2) with a pEC50 of 6.9. This compound demonstrates effective penetration of the blood-brain barrier, allowing for modulation of glutamate signaling within the central nervous system. GSK1331268 is suitable for research applications focused on neurodegenerative and neuropsychiatric disorders, providing valuable insight into potential therapeutic pathways.
Chemical Information
Catalog NumA61873
M. Wt342.83
FormulaC17H19ClN6
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1207197-70-3
Synonyms
SMILESClC1=CN=C(N2CCN(CC2)CC3=NC4=C(N3C)C=CC=C4)N=C1
Biological Activity
DescriptionGSK1331268 is a selective, orally active agonist of the metabotropic glutamate receptor 2 (mGluR2) with a pEC50 of 6.9. This compound demonstrates effective penetration of the blood-brain barrier, allowing for modulation of glutamate signaling within the central nervous system. GSK1331268 is suitable for research applications focused on neurodegenerative and neuropsychiatric disorders, providing valuable insight into potential therapeutic pathways.
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