Product Data Sheet
VU0418506
Catalog No. A61876
VU0418506 is a selective positive allosteric modulator of the metabotropic glutamate receptor 4 (mGlu4), displaying EC50 values of 68 nM and 46 nM for human and rat mGlu4, respectively. This compound demonstrates potential antiparkinsonian effects, making it a valuable tool for research into neurodegenerative disorders and related therapeutic avenues. Its specificity and efficacy make VU0418506 suitable for studies focused on modulation of glutamatergic signaling pathways in neurological contexts.
Chemical Information
| Catalog Num | A61876 |
|---|---|
| M. Wt | 262.67 |
| Formula | C12H8ClFN4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1330624-42-4 |
| Synonyms | |
| SMILES | FC1=CC=C(NC2=NNC3=C2N=CC=C3)C=C1Cl |
Biological Activity
| Description | VU0418506 is a selective positive allosteric modulator of the metabotropic glutamate receptor 4 (mGlu4), displaying EC50 values of 68 nM and 46 nM for human and rat mGlu4, respectively. This compound demonstrates potential antiparkinsonian effects, making it a valuable tool for research into neurodegenerative disorders and related therapeutic avenues. Its specificity and efficacy make VU0418506 suitable for studies focused on modulation of glutamatergic signaling pathways in neurological contexts. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
