Product Data Sheet

mGluR7 antagonist-2

Catalog No. A61877

main product photo
mGluR7 antagonist-2 is a potent and selective allosteric antagonist of the metabotropic glutamate receptor 7 (mGluR7), with an IC50 of 20 nM. This compound demonstrates significant selectivity for mGluR7 over other metabotropic glutamate receptors, including mGluR1, mGluR2, mGluR3, mGluR4, mGluR5, mGluR6, and mGluR8. mGluR7 antagonist-2 is valuable for research applications focusing on neuropharmacology and the investigation of glutamatergic signaling pathways.
Chemical Information
Catalog NumA61877
M. Wt302.33
FormulaC19H14N2O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.60986-80-3
Synonyms
SMILESO=C1C2=C(C=C(N1C)C3=CC=CC=C3)ON=C2C4=CC=CC=C4
Biological Activity
DescriptionmGluR7 antagonist-2 is a potent and selective allosteric antagonist of the metabotropic glutamate receptor 7 (mGluR7), with an IC50 of 20 nM. This compound demonstrates significant selectivity for mGluR7 over other metabotropic glutamate receptors, including mGluR1, mGluR2, mGluR3, mGluR4, mGluR5, mGluR6, and mGluR8. mGluR7 antagonist-2 is valuable for research applications focusing on neuropharmacology and the investigation of glutamatergic signaling pathways.
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