Product Data Sheet
JNJ-46356479
Catalog No. A61887
JNJ-46356479 is a selective positive allosteric modulator of the mGlu2 receptor, exhibiting an EC50 value of 78 nM. It demonstrates significant in vivo activity, making it a valuable compound for research into neurological disorders. This reagent is suitable for studies focused on enhancing glutamate signaling and understanding its implications in various therapeutic contexts.
Chemical Information
| Catalog Num | A61887 |
|---|---|
| M. Wt | 451.44 |
| Formula | C22H22F5N5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1254979-66-2 |
| Synonyms | |
| SMILES | FC1=CC=C(C(F)=C1)N2CCN(CC2)CC3=C(C4=NN=C(N4C=C3)CC5CC5)C(F)(F)F |
Biological Activity
| Description | JNJ-46356479 is a selective positive allosteric modulator of the mGlu2 receptor, exhibiting an EC50 value of 78 nM. It demonstrates significant in vivo activity, making it a valuable compound for research into neurological disorders. This reagent is suitable for studies focused on enhancing glutamate signaling and understanding its implications in various therapeutic contexts. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
