Product Data Sheet

Remeglurant

Catalog No. A61893

main product photo
Remeglurant is a selective, orally active allosteric antagonist of the metabotropic glutamate receptor 5 (mGlu5) with an IC50 of 13 nM. This compound demonstrates significant potential in advancing research related to dyskinesia in Parkinson's disease (PD). It is valuable for studies investigating the modulation of glutamatergic signaling and its impact on movement disorders.
Chemical Information
Catalog NumA61893
M. Wt371.23
FormulaC17H15BrN4O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1309783-00-3
SynonymsMRZ-8456
SMILESO=C(N1[C@@H](C2=C(CC1)C=CC=C2)C)C3=NN4C=C(C=NC4=C3)Br
Biological Activity
DescriptionRemeglurant is a selective, orally active allosteric antagonist of the metabotropic glutamate receptor 5 (mGlu5) with an IC50 of 13 nM. This compound demonstrates significant potential in advancing research related to dyskinesia in Parkinson's disease (PD). It is valuable for studies investigating the modulation of glutamatergic signaling and its impact on movement disorders.
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SHIPPING AND STORAGE
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